The group is now studying treatment with an intranasal form of pitocin in high-functioning adults with ASDs. "We're seeing that oxytocin delivered through the nose twice a day over a 6-week period has resulted in a reduction of self stimulatory behaviors and an improvement in social cognition," said Hollander.
Hollander's hypothesis that excess oxytocin (OT), possibly through OT administration at birth, could contribute to the development of autistic spectrum disorders and related syndromes by proposed down regulation of the OT receptor (OTR).
On the other hand, a Japanese obstetric study has suggested that the administration of oxytocin to mothers during birth may actually contribute to autistic problems later in life. We are presently conducting a large developmental study where we administered newborn rat pups very high doses of oxytocin directly into the brain for the first few days of life. We have yet seen anything that give us any reason for concern about this causing autistic-like behavior pattern.
So what effect would oxytocin have if taken recreationally in humans? Panksepp has tried taking it and says he felt only a mild effect. "I seemed to be in a more relaxed 'in the moment' mood, with a greater confidence and appreciation of my connectedness to other people and nature," he says. Most people, however, cannot tell whether they've been given oxytocin or a placebo. Women seem slightly more likely to report subjective effects like calmness, according to Panksepp. Hollander, meanwhile, says his subjects experience "no rush, high or euphoria".
たいしたことは起こらんようだw appreciation of my connectedness to other people and nature これなんかは アスペが感じることはまずないと思うが・・・ 感じたりしたら 効果があったことになるかもw
Zusammensetzung Wirkstoff: Oxytocinum. Ampullen (1 ml) zu 5 I.E./ml. Hilfsstoffe: Natrii acetas, Ethanolum, Conserv.: Chlorobutanolum hemihydricum 5 mg, Aqua q.s. ad sol. pro 1 ml. Spray (5 ml) zu 40 I.E./ml. Hilfsstoffe: Conserv.: E 216, E 218, Chlorobutanolum hemihydricum, Excip. ad sol. pro 1 ml.
Haltbarkeit Syntocinon soll im Kühlschrank (2-8 °C) aufbewahrt werden. Nach dem Öffnen soll die Sprayflasche bei Zimmertempertur aufbewahrt und nicht länger als 1 Monat verwendet werden.